Cpap And Acid Reflux Aspiration

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Medically reviewed by Drugs.com. Last updated on for 1 last update 05 Aug 2020 Apr 17, 2019. Medically reviewed by Drugs.com. Last updated on Apr 17, 2019.

In Summary

Commonly reported side effects of ibrutinib include: infection, anemia, neutropenia, thrombocytopenia, bruise, and cytopenia. Other side effects include: malignant neoplasm, malignant neoplasm of skin, subdural hematoma, gastrointestinal hemorrhage, and hematuria. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to ibrutinib: oral capsule, oral tablet

Side effects requiring immediate medical attention

Along with its needed effects, ibrutinib may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ibrutinib:

More common

  • Back pain
  • bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or black, tarry stools
  • bloody or cloudy urine
  • blurred vision
  • body aches or pain
  • chest pain
  • chills
  • confusion
  • cough
  • decreased frequency or amount of urine
  • difficult, burning, or painful urination
  • dizziness or lightheadedness
  • drowsiness
  • dry mouth
  • fainting
  • fast or irregular heartbeat
  • fever
  • frequent urge to urinate
  • headache
  • hoarseness
  • increased thirst
  • irregular heartbeat
  • itching
  • loss of appetite
  • lower back or side pain
  • nausea
  • rapid weight gain
  • seizures
  • severe headache
  • severe stomach pain
  • sore throat
  • tightness of the chest
  • tingling of the hands or feet
  • troubled breathing
  • ulcers, sores, or white spots in the mouth
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting
  • vomiting of blood or material that looks like coffee grounds
  • wrinkled skin

Less common

  • Persistent non-healing sore
  • pink skin growth
  • reddish skin patch or irritated area
  • shiny skin bump
  • white, yellow or waxy scar-like area on the skin

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  • Blistering, peeling, or loosening of the skin
  • dark urine
  • diarrhea
  • difficulty swallowing
  • general feeling of tiredness or weakness
  • hives, skin rash
  • joint pain, stiffness, or swelling
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  • light-colored stools
  • muscle pain
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • yellow eyes or skin

Side effects not requiring immediate medical attention

Some side effects of ibrutinib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Belching
  • decreased appetite
  • difficulty having a bowel movement
  • heartburn or indigestion
  • indigestion
  • lack or loss of strength
  • muscle stiffness or spasms
  • small red or purple spots on the skin
  • stomach discomfort, upset, or pain
  • swelling or inflammation of the mouth

For Healthcare Professionals

Applies to ibrutinib: oral capsule, oral tablet

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Cpap And Acid Reflux Aspiration Unexpected Foods (πŸ”₯ Without Medication) | Cpap And Acid Reflux Aspiration Diagnosishow to Cpap And Acid Reflux Aspiration for Very common (10% or more): Hypertension (17%)

Common (1% to 10%): Atrial fibrillation, atrial flutter[Ref]

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-Lymphocytosis occurred in up to 77% of treated patients. Typical onset of isolated lymphocytosis was within the first month of starting the 1 last update 05 Aug 2020 the drug and resolved approximately at 8 weeks. -Lymphocytosis occurred in up to 77% of treated patients. Typical onset of isolated lymphocytosis was within the first month of starting the drug and resolved approximately at 8 weeks.

-Bleeding events occurred in up to 50% of treated patients. Bleeding events ranged from minor hemorrhagic events such as petechiae and contusions to Grade 3 or higher bleeding events. Approximately 6% of patients experienced a Grade 3 or higher bleeding event including cases of subdural hematoma, gastrointestinal bleeding, hematuria and post procedural hemorrhage

-Treatment-emergent Grade 3 or 4 cytopenias included neutropenia (19% to 29%), thrombocytopenia (5% to 17%), and anemia (0 to 9%).[Ref]

Very common (10% or more): Lymphocytosis (77%), decreased platelets (71%), decreased neutrophils (54%), bleeding events (all grades; approximately 50%), decreased hemoglobin (44%), neutropenia (29%), thrombocytopenia (17%)

Common (1% to 10%): Bleeding events, anemia, febrile neutropenia

Uncommon (less than 1%): Leukostasis

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Hypersensitivity

Postmarketing reports: Anaphylactic shock (fatal), urticaria, angioedema[Ref]

Immunologic

Frequency not reported: Progressive multifocal leukoencephalopathy (PML)[Ref]

Grade 3 or higher infections including urinary tract infection, pneumonia, skin infections, and sinusitis were reported.[Ref]

Musculoskeletal

Very common (10% or more): Musculoskeletal pain (37%), arthralgia (23%), muscle spasms (19%)[Ref]

Ocular

Very common (10% or more): Blurred vision (10%)[Ref]

Metabolic

Very common (10% or more): Elevated uric acid levels (40%), decreased appetite (21%), hyperuricemia (15%), dehydration (12%)

Frequency not reported: Tumor lysis syndrome[Ref]

Psychiatric

Very common (10% or more): Anxiety (10%), insomnia (10%)[Ref]

Genitourinary

Very common (10% or more): Urinary tract infection (14%)[Ref]

Oncologic

Very common (10% or more): Second primary malignancies (10%)

Common (1% to 10%): Non-melanoma skin cancer, carcinomas[Ref]

Respiratory

Very common (10% or more): Upper respiratory tract infection (up to 48%), dyspnea (up to 27%), sinusitis (up to 21%), cough (up to 19%), oropharyngeal pain (up to 15%), pneumonia (up to 15%), epistaxis (up to 11%)[Ref]

Other

Very common (10% or more): Fatigue (41%), peripheral edema (35%), pyrexia (25%), asthenia (14%), chills (13%)

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General

The most commonly for 1 last update 05 Aug 2020 occurring adverse reactions (25% or more) included thrombocytopenia, neutropenia, diarrhea, anemia, fatigue, musculoskeletal pain, bruising, nausea, upper respiratory tract infection, and rash.[Ref]The most commonly occurring adverse reactions (25% or more) included thrombocytopenia, neutropenia, diarrhea, anemia, fatigue, musculoskeletal pain, bruising, nausea, upper respiratory tract infection, and rash.[Ref]

Nervous system

Very common (10% or more): Dizziness (21%), headache (19%), peripheral neuropathy (10%)

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Cpap And Acid Reflux Aspiration 7 Home Remedies (πŸ”₯ Breakfast For) | Cpap And Acid Reflux Aspiration Without Medicationhow to Cpap And Acid Reflux Aspiration for Frequency not reported: Intracranial hemorrhage, lethargy[Ref]

Renal

Very common (14%): Urinary tract infection

Common (1% to 10%): Increased creatinine

Frequency not reported: Renal failure (fatal and serious cases)[Ref]

Fatal and serious cases of renal failure have been reported. Increases in creatinine 1.5 to 3 times the upper limit of normal have been observed (9%).[Ref]

Dermatologic

petechiae (17%), contusion (11%), laceration (10%)[Ref]petechiae (17%), contusion (11%), laceration (10%)[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (63%), nausea (31%), constipation (25%), abdominal pain (24%), vomiting (23%), stomatitis (21%), dyspepsia (13%)Very common (10% or more): Diarrhea (63%), nausea (31%), constipation (25%), abdominal pain (24%), vomiting (23%), stomatitis (21%), dyspepsia (13%)

Common (1% to for 1 last update 05 Aug 2020 10%): Dry mouth[Ref]Common (1% to 10%): Dry mouth[Ref]

References

1. "" Pharmacyclics Inc, Sunnyvale, CA.

Cpap And Acid Reflux Aspiration Foods For Acid Reflux (πŸ”΄ Heartburn During Pregnancy) | Cpap And Acid Reflux Aspiration Heartburn Remedieshow to Cpap And Acid Reflux Aspiration for 2. Cerner Multum, Inc. "" O 0

3. Cerner Multum, Inc. "" O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Related questions

Medical Disclaimer

More about ibrutinib

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Other brands: Imbruvica

Professional resources

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Drug Status

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User Reviews & Ratings

Ibrutinib reviews

6.4 / 10 35 Reviews
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